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Genome-wide methylation comparisons between 65 DS and 59 NS healthcare workers revealed 21 loci in circadian genes, including PER3 and CSNK1E, to be significantly hypomethylated among NSW, highlighting potential epigenetic mechanisms underlying shift work-associated disease risk 214
Chen L, Shi X-J, Liu H, Mao X, Gui L-N, Wang H, et al
doi: 10.1056/NEJM198812293192602 145 GoldDBowdenRSixbeyJRiggsRKatonWJAshleyRet al
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